A steadfast commitment to Vitamin K2 research and development assures MenaQ7® is a superior product based on the following important criteria:
- High Purity
An essential characteristic of a superior Vitamin K2 ingredient is the level of purity, which is important for the overall quality and efficacy of the end product.
Products with a high level of unknowns or impurities offer less of the beneficial effects of the MK-7 molecule. That is not the case with MenaQ7®. For example, MenaQ7® PURE, the nature–identical synthetic Vitamin K2, has more than 98% MK-7, making it a uniquely concentrated and pure material.
Every batch of MenaQ7® produced is controlled by HPLC.
- All-trans MK-7:
Natural vitamin K occurs in the all-trans configuration12, which has been proven to be the biologically active form13 – meaning that this configuration will activate the carboxylase enzyme, enabling it to further activate proteins like coagulation factors, Osteocalcin, and MGP, among others.
Research has established the efficacy of the trans–form, while the cis–isomers benefit and activity in the body is unknown.14
MenaQ7® is an all-trans form of Vitamin K2 as MK-7.
Both sources of MenaQ7® materials are given Novel Food status by the European Food Safety Authority (EFSA). The scientific safety evaluation performed by EFSA is a solid confirmation to the public that the product is safe and beneficial.
MenaQ7® is also self-affirmed GRAS (generally recognized as safe) in the United States, a designation by the U.S. Food and Drug Administration (FDA) stating that all necessary research, including the formation of an expert panel to review safety concerns, has been performed.
Recommended daily intake of vitamin K is 120 mcg/day (US) for men, 90 mcg/day (US) for women, and 30-55 mcg/day (US) for children.
A dose and safety study done by Theuwissen et al (2012)15 showed that extra intake of MK-7, as MenaQ7®, at nutritional doses around RDI improved the activation of proteins like Osteocalcin and Matrix Gla. No adverse effects of thrombin was observed.
NOTE: Vitamin K is needed for proper activation of several coagulation (blood-clotting) proteins, which is why it is recommended that patients receiving oral-anticoagulant (OAC) treatment do not take MK-7 supplements without consulting with their medical doctor.