Absorption and half-life time

Both vitamin K2 supplements are nearly completely absorbed, with peak serum concentration at 2 hours for MK-4 and 4 hours for MK-7 after intake. However, MK-4 quickly disappears from the circulation (after approx. 8 hours), whereas MK-7 is capable of accumulating in the bloodstream (remains in the body for approx. 72 hours). Supplementation with MK-7 only needs to be taken once a day and is therefore more convenient.⁵⁷